Ronald A, Gordon JA, Andlauer TFM, Atwoli A, Cai N, Lehner T, Nivard MG, Roeder K (2023): Exploring and Exploiting Genetic Risk for Psychiatric Disorders. Chapter 2: Delineating Additional Risk Factors. The MIT Press – Strüngmann Forum Reports doi:10.7551/mitpress/15380.001.0001; ISBN: 9780262377423 Edited by: Joshua A. Gordon, Elisabeth B. Binder View book chapter
Gasperi C, Wiltgen T, McGinnis J, Cerri S, Moridi T, Ouellette R, Pukaj A, Voon C, Bafligil C, Lauerer M, Andlauer TFM, Held F, Aly L, Shchetynsky K, Stridh P, Harroud A, Wiestler B, Kirschke JS, Zimmer C, Baras A, Piehl F, Berthele A, Granberg T, Kockum I, Hemmer B, Mühlau M (2023): A Genetic Risk Variant for Multiple Sclerosis Severity is Associated with Brain Atrophy. Annals of Neurology doi:10.1002/ana.26807 View article
Amare AT, Thalamuthu A, Schubert KO, …, Andlauer TFM, …, Schulze TG, Clark SR, Baune BT (2023): Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder. Molecular Psychiatry doi:10.1038/s41380-023-02149-1 View article
International Multiple Sclerosis Genetics Consortium: Harroud A, Stridh P, McCauley JL, Saarela J, van den Bosch AMR, Engelenburg HJ, Beecham AH, Alfredsson L, Alikhani K, Amezcua L, Andlauer TFM, …, Sawcer SJ, Baranzini SE; MultipleMS (2023): Locus for severity implicates CNS resilience in progression of multiple sclerosis. Nature 619(7969):323-331 View article
Mascheretti S, Forni D, Lampis V, Fumagalli L, Paquin S, Andlauer TFM, Wang W, Dionne G, Brendgen MR, Vitaro F, Ouellet-Morin I, Rouleau G, Gouin JP, Côté S, Tremblay RE, Turecki G, Garon-Carrier G, Boivin M, Battaglia M (2023): Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis. PLOS ONE 18(5):e0285263 View article
Zheng J, Wheeler E, Pietzner M, Andlauer TFM, Yau MS, Hartley AE, Brumpton BM, Rasheed H, Kemp JP, Frysz M, Robinson J, Reppe S, Prijatelj V, Gautvik KM, Falk L, Maerz W, Gergei I, Peyser PA, Kavousi M, de Vries PS, Miller CL, Bos M, van der Laan SW, Malhotra R, Herrmann M, Scharnagl H, Kleber M, Dedoussis G, Zeggini E, Nethander M, Ohlsson C, Lorentzon M, Wareham N, Langenberg C, Holmes MV, Davey Smith G, Tobias JH (2023): Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization. Arthritis & Rheumatology doi:10.1002/art.42538 View article
Slosarek T*, Ibing S*, Schormair B, Heyne HO, Böttinger EP, Andlauer TFM*, Schurmann C* (2023): Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities. BMC Medical Genomics 16(1):73 View article
David FS, Stein F, Andlauer TFM, Streit F, Witt SH, Herms S, Hoffmann P, Heilmann-Heimbach S, Opel N, Repple J, Jansen A, Nenadić I, Papiol S, Heilbronner U, Kalman JL, Schaupp SK, Senner F, Schulte EC, Falkai PG, Schulze TG, Dannlowski U, Kircher T, Rietschel M, Nöthen MM, Krug A, Forstner AJ (2023): Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders. Schizophrenia Research 252:161-171 View article
Hahn T, Winter NR, Ernsting J, Gruber M, Mauritz MJ, Fisch L, Leenings R, Sarink K, Blanke J, Holstein V, Emden D, Beisemann M, Opel N, Grotegerd D, Meinert S, Heindel W, Witt S, Rietschel M, Nöthen MM, Forstner AJ, Kircher T, Nenadic I, Jansen A, Müller-Myhsok B, Andlauer TFM, Walter M, van den Heuvel MP, Jamalabadi H, Dannlowski U, Repple J (2023): Genetic, individual, and familial risk correlates of brain network controllability in major depressive disorder. Molecular Psychiatry doi:10.1038/s41380-022-01936-6 View article
Oraki Kohshour M, Schulte EC, Heilbronner U, Budde M, Kalman JL, Senner F, Heilbronner M, Reich-Erkelenz D, Schaupp SK, Vogl T, Adorjan K, Anghelescu IG, Arolt V, Baune BT, Dannlowski U, Dietrich D, Fallgatter A, Figge C, Jäger M, Lang FU, Juckel G, Konrad C, Reimer J, Reininghaus EZ, Schmauß M, Spitzer C, von Hagen M, Wiltfang J, Zimmermann J, Andlauer TFM, Nöthen MM, Degenhardt F, Forstner AJ, Rietschel M, Witt SH, Fischer A, Falkai P, Papiol S, Schulze TG (2023): Association between mitochondria-related genes and cognitive performance in the PsyCourse Study. Journal of Affective Disorders doi:10.1016/j.jad.2023.01.013 View abstract
One additional publication as part of the MDD Working Group of the Psychiatric Genomics Consortium:
Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability. American Journal of Human Genetics 110(7):1207-1215 View article
2022
Tielbeek JJ, Uffelmann E, Williams BS, …, Andlauer TFM, …, Caspi A, Polderman TJC, Posthuma D (2022): Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis. Molecular Psychiatry doi:10.1038/s41380-022-01793-3 View article
Perret LC, Boivin M, Morneau-Vaillancourt G, Andlauer TFM, Paquin S, Langevin S, Girard A, Turecki G, O’Donnell K, Tremblay RE, Côté SM, Gouin JP, Ouellet-Morin I, Geoffroy MC (2022): Polygenic risk score and peer victimisation independently predict depressive symptoms in adolescence: results from the Quebec Longitudinal Study of Children Development. J Child Psychol Psychiatry doi:10.1111/jcpp.13706 View article
Eising E, Mirza-Schreiber N, de Zeeuw EL, …, Andlauer TFM, …, St Pourcain B, Francks C, Fisher SE (2022): Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people. PNAS 119(35):e2202764119 View article
Winter NR, Leenings R, Ernsting J, Sarink K, Fisch L, Emden D, Blanke J, Goltermann J, Opel N, Barkhau C, Meinert S, Dohm K, Repple J, Mauritz M, Gruber M, Leehr EJ, Grotegerd D, Redlich R, Jansen A, Nenadic I, Nöthen MM, Forstner A, Rietschel M, Groß J, Bauer J, Heindel W, Andlauer TFM, Eickhoff SB, Kircher T, Dannlowski U, Hahn T (2022): Quantifying Deviations of Brain Structure and Function in Major Depressive Disorder Across Neuroimaging Modalities. JAMA Psychiatry doi: 10.1001/jamapsychiatry.2022.1780 View article
Kalman JL, Yoshida T, Andlauer TFM, Schulte EC, Adorjan K, Alda M, Ardau R, Aubry JM, Brosch K, Budde M, Chillotti C, Czerski PM, DePaulo RJ, Forstner A, Goes FS, Grigoroiu-Serbanescu M, Grof P, Grotegerd D, Hahn T, Heilbronner M, Hasler R, Heilbronner U, Heilmann-Heimbach S, Kapelski P, Kato T, Kohshour MO, Meinert S, Meller T, Nenadić I, Nöthen MM, Novak T, Opel N, Pawlak J, Pfarr JK, Potash JB, Reich-Erkelenz D, Repple J, Richard-Lepouriel H, Rietschel M, Ringwald KG, Rouleau G, Schaupp S, Senner F, Severino G, Squassina A, Stein F, Stopkova P, Streit F, Thiel K, Thomas-Odenthal F, Turecki G, Twarowska-Hauser J, Winter A, Zandi PP, Kelsoe JR; Consortium on Lithium Genetics (ConLiGen), PsyCourse, Falkai P, Dannlowski U, Kircher T, Schulze TG, Papiol S (2022): Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses. Eur Arch Psychiatry Clin Neurosci doi 10.1007/s00406-021-01366-5 View article
Gergei I*, Zheng J*, Andlauer TFM* (shared first), Brandenburg V, Mirza-Schreiber N, Müller-Myhsok B, Krämer BK, Richard D, Falk L, Movérare-Skrtic S, Ohlsson C, Smith GD, März W, Voelkl J, Tobias JH (2022): GWAS meta-analysis followed by Mendelian randomisation revealed potential control mechanisms for circulating α-klotho levels. Human Molecular Genetics 31(5):792-802 View article
Kalman JL, Papiol S, Grigoroiu-Serbanescu M, Adorjan K, Anderson-Schmidt H, Brosch K, Budde M, Comes AL, Gade K, Forstner A, Grotegerd D, Hahn T, Heilbronner M, Heilbronner U, Heilmann-Heimbach S, Klöhn-Saghatolislam F, Kohshour MO, Meinert S, Meller T, Mullins N, Nenadić I, Nöthen MM, Pfarr JK, Reich-Erkelenz D, Rietschel M, Ringwald KG, Schaupp S, Schulte EC, Senner F, Stein F, Streit F, Vogl T, Falkai P, Dannlowski U, Kircher T, Schulze TG, Andlauer TFM (2022): Genetic risk for psychiatric illness is associated with the number of hospitalizations of bipolar disorder patients. Journal of Affective Disorders 296:532-540 View article
Two additional publications as part of the MDD Working Group of the Psychiatric Genomics Consortium:
Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry Global Open Science 2(2):115-126 View article
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry 91(3):313-327 View article
Two additional publications as part of the GenLang Consortium:
Discovery of 42 genome-wide significant loci associated with dyslexia. Nature Genetics 54:1621-1629 View article
Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities Translational Psychiatry 12(1):495 View article
2021
Kalman JL, Olde Loohuis LM, Vreeker A, …, …, Andlauer TFM*, Schulze TG*, Ophoff RA* (shared last) (2021): Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry 219, 659–669 View article
Heilbronner U, Streit F, Vogl T, Senner F, Schaupp SK, Reich-Erkelenz D, Papiol S, Kohshour MO, Klöhn-Saghatolislam F, Kalman JL, Heilbronner M, Gade K, Comes AL, Budde M, Andlauer TFM, Anderson-Schmidt H, Adorjan K, Stürmer T, Loerbroks A, Amelang M, Poisel E, Foo J, Heilmann-Heimbach S, Forstner AJ, Degenhardt F, Zimmermann J, Wiltfang J, von Hagen M, Spitzer C, Schmauss M, Reininghaus E, Reimer J, Konrad C, Juckel G, Lang FU, Jäger M, Figge C, Fallgatter AJ, Dietrich DE, Dannlowski U, Baune BT, Arolt V, Anghelescu IG, Nöthen MM, Witt SH, Andreassen OA, Chen CH, Falkai P, Rietschel M, Schulze TG, Schulte EC (2021): Interplay between the Genetics of Personality Traits, severe Psychiatric Disorders, and COVID-19 Host Genetics in the Susceptibility to SARS-CoV-2 Infection. BJPsych Open7(6), E188 View article
Andlauer TFM (2021): Influence of genetic factors on disorders of the central nervous system Habilitation thesis, School of Medicine, Technical University of Munich Download at mediaTUM
Smigielski L, Papiol S, Theodoridou A, Heekeren K, Gerstenberg M, Wotruba D, Buechler R, Hoffmann P, Herms S, Adorjan K, Anderson-Schmidt H, Budde M, Comes AL, Gade K, Heilbronner M, Heilbronner U, Kalman JL, Klöhn-Saghatolislam F, Reich-Erkelenz D, Schaupp SK, Schulte EC, Senner F, Anghelescu IG, Arolt V, Baune BT, Dannlowski U, Dietrich DE, Fallgatter AJ, Figge C, Jäger M, Juckel G, Konrad C, Nieratschker V, Reimer J, Reininghaus E, Schmauß M, Spitzer C, von Hagen M, Wiltfang J, Zimmermann J, Gryaznova A, Flatau-Nagel L, Reitt M, Meyers M, Emons B, Haußleiter IS, Lang FU, Becker T, Wigand ME, Witt SH, Degenhardt F, Forstner AJ, Rietschel M, Nöthen MM, Andlauer TFM, Rössler W, Walitza S, Falkai P, Schulze TG, Grünblatt E (2021): Polygenic risk scores across the extended psychosis spectrum. Translational Psychiatry 11(1):600 View article
Bussas M, Grahl S, Pongratz V, Berthele A, Gasperi C, Andlauer TFM, Gaser C, Kirschke JS, Wiestler B, Zimmer C, Hemmer B, Mühlau M (2021): Gray matter atrophy in relapsing-remitting multiple sclerosis is associated with white matter lesions in connecting fibers. Multiple Sclerosis 28(6):900-909 View article
Cirac A, Tsaktanis T, Beyer T, Linnerbauer M, Andlauer TFM, Grummel V, Nirschl L, Loesslein L, Quintana FJ, Hemmer B, Rothhammer V (2021): The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. Neurology Neuroimmunology & Neuroinflammation 8(5):e1043 View article
Wendel B, Papiol S, Andlauer TFM, Zimmermann J, Wiltfang J, Spitzer C, Senner F, Schulte EC, Schmauß M, Schaupp SK, Repple J, Reininghaus E, Reimer J, Reich-Erkelenz D, Opel N, Nenadić I, Meinert S, Konrad C, Klöhn-Saghatolislam F, Kircher T, Kalman JL, Juckel G, Jansen A, Jäger M, Heilbronner M, von Hagen M, Gade K, Figge C, Fallgatter AJ, Dietrich DE, Dannlowski U, Comes AL, Budde M, Baune BT, Arolt V, Anghelescu IG, Anderson-Schmidt H, Adorjan K, Falkai P, Schulze TG, Bickeböller H, Heilbronner U (2021): A genome-wide association study of the longitudinal course of executive functions. Translational Psychiatry 11(1):386 View article
Ringwald KG, Meller T, Schmitt S, Andlauer TFM, Stein F, Brosch K, Pfarr JK, Steinsträter O, Meinert S, Lemke H, Waltemate L, Thiel K, Grotegerd D, Enneking V, Klug M, Jansen A, Forstner AJ, Streit F, Witt SH, Rietschel M, Müller-Myhsok B, Nöthen MM, Dannlowski U, Krug A, Nenadić I, Kircher T (2021): Interaction of developmental factors and ordinary stressful life events on brain structure in adults. NeuroImage: Clinical 30:102683 View article
Pelin H, Ising M, Stein F, Meinert S, Meller T, Brosch K, Winter NR, Krug A, Leenings R, Lemke H, Nenadić I, Heilmann-Heimbach S, Forstner AJ, Nöthen MM, Opel N, Repple J, Pfarr J, Ringwald K, Schmitt S, Thiel K, Waltemate L, Winter A, Streit F, Witt S, Rietschel M, Dannlowski U, Kircher T, Hahn T, Müller-Myhsok B, Andlauer TFM (2021): Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning. Neuropsychopharmacology 46, 1895-1905 View article
Morneau-Vaillancourt G, Andlauer TFM, Ouellet-Morin I, Paquin S, Brendgen MR, Vitaro F, Gouin JP, Séguin JR, Gagnon É, Cheesman R, Forget-Dubois N, Rouleau GA, Turecki G, Tremblay RE, Côté SM, Dionne G, Boivin M (2021): Polygenic scores differentially predict developmental trajectories of subtypes of social withdrawal in childhood. The Journal of Child Psychology and Psychiatry 62(11):1320-1329 View article
Zeng L, Moser S, Mirza-Schreiber N, Lamina C, Coassin S, Nelson CP, Annilo T, Franzén O, Kleber ME, Mack S, Andlauer TFM, Jiang B, Stiller B, Li L, Willenborg C, Munz M, Kessler T, Kastrati A, Laugwitz KL, Erdmann J, Moebus S, Nöthen MM, Peters A, Strauch K, Müller-Nurasyid M, Gieger C, Meitinger T, Steinhagen-Thiessen E, März W, Metspalu A, Björkegren JLM, Samani NJ, Kronenberg F, Müller-Myhsok B, Schunkert H (2021): Cis-epistasis at the LPA locus and risk of cardiovascular diseases. Cardiovascular Research doi: 10.1093/cvr/cvab136 View article
Andlauer TFM, Mühleisen TW, Hoffstaedter F, Teumer A, Wittfeld K, Teuber A, Reinbold CS, Grotegerd D, Bülow R, Caspers S, Dannlowski U, Herms S, Hoffmann P, Kircher T, Minnerup H, Moebus S, Nenadić I, Teismann H, Völker U, Etkin A, Berger K, Grabe HJ, Nöthen MM, Amunts K, Eickhoff SB, Sämann PG, Müller-Myhsok B, Cichon S (2021): Genetic factors influencing a neurobiological substrate for psychiatric disorders. Translational Psychiatry 11(1):192 View article
Vandebergh M, Andlauer TFM, Zhou Y, Mallants K, Held F, Aly L, Taylor BV, Hemmer B, Dubois B, Goris A (2021): Genetic variation in WNT9B increases relapse hazard in multiple sclerosis. Annals of Neurology doi: 10.1002/ana.26061 View article
Kendall KM, van Assche E, Andlauer TFM, Choi KW, Luykx JJ, Schulte EC, Lu Y (2021): The genetic basis of major depression. Psychological Medicine 51(13), 2217-2230 View article
Heilbronner U, Papiol S, Budde M, Andlauer TFM, Strohmaier J, Streit F, Frank J, Degenhardt F, Heilmann-Heimbach S, Witt SH, Forstner AJ, Loerbroks A, Amelang M, Stürmer T, Müller-Myhsok B, Nöthen MM, Rietschel M, Schulze TG (2021): “The Heidelberg Five” personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment. Med Genet B Neuropsychiatr Genet doi: 10.1002/ajmg.b.32837 View article
Guzman-Parra J, Streit F, Forstner AJ, Strohmaier J, González MJ, Gil Flores S, Cabaleiro Fabeiro FJ, del Río Noriega F, Perez Perez F, Haro González J, Orozco Diaz G, de Diego-Otero Y, Moreno-Kuestner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Sirignano L, Witt SH, Cichon C, Rivas F, Mayoral F, Nöthen MM, Andlauer TFM*, Rietschel M* (shared last) (2021): Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families. Translational Psychiatry 11(1):31 View article
Ostkamp P, Salmen A, Pignolet B, Görlich D, Andlauer TFM, Schulte-Mecklenbeck A, Gonzalez-Escamilla G, Bucciarelli F, Gennero I, Breuer J, Antony G, Schneider-Hohendorf T, Mykicki N, Bayas A, Then Bergh F, Bittner S, Hartung HP, Friese MA, Linker RA, Luessi F, Lehmann-Horn K, Mühlau M, Paul F, Stangel M, Tackenberg B, Tumani H, Warnke C, Weber F, Wildemann B, Zettl UK, Ziemann U, Müller-Myhsok B, Kümpfel T, Klotz L, Meuth SG, Zipp F, Hemmer B, Hohlfeld R, Brassat D, Gold R, Gross CC, Lukas C, Groppa S, Loser K, Wiendl H, Schwab N; German Competence Network Multiple Sclerosis (KKNMS) and the BIONAT Network (2021): Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity. PNAS 118(1):e2018457118 View article
Three additional publications as part of the MDD Working Group of the Psychiatric Genomics Consortium:
The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study. JAMA Psychiatry e212099 View abstract
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry 91(1):102-117 View abstract
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts. Biological Psychiatry 90(9):611-620 View abstract
