Publications 2019-2020

Colour code:
  • Yellow: highlighted first-/last-author publications
  • Blue: other especially highlighted publications

2020

  • Heitmann H, Andlauer TFM, Korn T, Mühlau M, Henningsen P, Hemmer B, Ploner M. (2020):
    Fatigue, depression, and pain in multiple sclerosis: How neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms.
    Multiple Sclerosis Journal doi:10.1177/1352458520972279
    View article
  • Andlauer TFM, Link J, Martin D, Ryner M, Hermanrud C, Grummel V, Auer M, Hegen H, Aly L, Gasperi C, Knier B, Müller-Myhsok B, Jensen PEH, Sellebjerg F, Kockum I, Olsson T, Pallardy M, Spindeldreher S, Deisenhammer F, Fogdell-Hahn A, Hemmer B & on behalf of the ABIRISK consortium (2020):
    Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS.
    BMC Medicine 18:298
    View article
  • Gialluisi A, Andlauer TFM, Mirza-Schreiber N, Moll K, Becker J, Hoffmann P, Ludwig KU, Czamara D, St Pourcain B, Honbolygó F, Tóth D, Csépe V, Huguet G, Chaix Y, Iannuzzi S, Demonet J, Morris AP, Hulslander J, Willcutt EJ, DeFries JC, Olson RK, Smith SD, Pennington BF, Vaessen A, Maurer U, Lyytinen H, Peyrard-Janvid M, Leppänen PHT, Brandeis D, Bonte M, Stein JF, Talcott JB, Fauchereau F, Wilcke A, Kirsten H, Müller B, Francks C, Bourgeron T, Monaco AP, Ramus F, Landerl K, Kere J, Scerri TS, Paracchini S, Fisher SE, Schumacher J, Nöthen MM, Müller-Myhsok B & Schulte-Körne B (2020):
    Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia.
    Molecular Psychiatry 26(7):3004-3017
    View article
  • Faber H, Kurtoic D, Krishnamoorthy G, Weber P, Pütz P, Müller-Myhsok B, Weber F, Andlauer TFM (2020):
    Gene Expression in Spontaneous Experimental Autoimmune Encephalomyelitis Is Linked to Human Multiple Sclerosis Risk Genes.
    Frontiers in Immunology 11:2165
    View article
  • Goltermann J, Redlich R, Grotegerd D, Dohm K, Leehr EJ, Böhnlein J, Förster K, Meinert S, Enneking V, Richter M, Repple J, DeVillers I, Kloecker M, Jansen A, Krug A, Nenadić I, Brosch K, Meller T, Stein F, Schmitt S, Rietschel M, Streit F, Witt SH, Forstner AJ, Nöthen MM, Baune BT, Andlauer TFM, Kircher T, Opel N, Dannlowski U (2020):
    Childhood maltreatment and cognitive functioning: the role of depression, parental education, and polygenic predisposition.
    Neuropsychopharmacology doi:10.1038/s41386-020-00794-6
    View article
  • Andlauer TFM, Nöthen MM (2020):
    Polygenic scores for psychiatric disease: from research tool to clinical application.
    medizinische genetik 32(1) 39-45
    View article
  • Nenadić I, Meller T, Schmitt S, Stein F, Brosch K, Mosebach J, Ettinger U, Grant P, Meinert S, Opel N, Lemke H, Fingas S, Förster K, Hahn T, Jansen A, Andlauer TFM, Forstner AJ, Heilmann-Heimbach S, Hall ASM, Awasthi S, Ripke S, Witt SH, Rietschel M, Müller-Myhsok B, Nöthen MM, Dannlowski U, Krug A, Streit F, Kircher T (2020):
    Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects.
    Psychological Medicine doi:10.1017/S0033291720002822
    View abstract
  • Gasperi C, Andlauer TFM, Keating A, Knier B, Klein A, Pernpeintner V, Lichtner P, Gold R, Zipp F, Then Bergh F, Stangel M, Tumani H, Wildemann B, Wiendl H, Bayas A, Kümpfel T, Zettl UK, Linker RA, Ziemann U, Knop M, Warnke C, Friese MA, Paul F, Tackenberg B, Berthele A, Hemmer B (2020):
    Genetic determinants of the humoral immune response in MS.
    Neurology Neuroimmunology & Neuroinflammation 7(5):e827
    View abstract
  • Hagenaars SP, Coleman JRI, Choi SW, Gaspar H, Adams MJ, Howard DM, Hodgson K, Traylor M, Air TM, Andlauer TFM, Arolt V, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Campbell A, Cearns M, Czamara D, Dannlowski U, Domschke K, de Geus EJC, Hamilton SP, Hayward C, Hickie IB, Hottenga JJ, Ising M, Jones I, Jones L, Kutalik Z, Lucae S, Martin NG, Milaneschi Y, Mueller-Myhsok B, Owen MJ, Padmanabhan S, Penninx BWJH, Pistis G, Porteous DJ, Preisig M, Ripke S, Shyn SI, Sullivan PF, Whitfield JB, Wray NR, McIntosh AM, Deary IJ, Breen G, Lewis CM (2020):
    Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.
    American Journal of Medical Genetics Part B: Neuropsychiatric Genetics doi:10.1002/ajmg.b.32807
    View abstract
  • Aly L, Havla J, Lepennetier G, Andlauer TFM, Sie C, Strauß EM, Hoshi MM, Kümpfel T, Hiltensperger M, Mitsdoerffer M, Mühlau M, Zimmer C, Hemmer B, Korn T, Knier B (2020):
    Inner retinal layer thinning in radiologically isolated syndrome predicts conversion to multiple sclerosis.
    European Journal of Neurology doi:10.1111/ene.14416
    View abstract
  • Krug A, Wöhr M, Seffer D, Rippberger H, Sungur AÖ, Dietsche B, Stein F, Sivalingam S, Forstner AJ, Witt SH, Dukal H, Streit F, Maaser A, Heilmann-Heimbach S, Andlauer TFM, Herms S, Hoffmann P, Rietschel M, Nöthen MM, Lackinger M, Schratt G, Koch M, Schwarting RKW, Kircher T (2020):
    Advanced paternal age as a risk factor for neurodevelopmental disorders: a translational study.
    Molecular Autism 11(1):54
    View abstract
  • Cai N, Revez JA, Adams MJ, Andlauer TFM, Breen G, Byrne EM, Clarke TK, Forstner AJ, Grabe HJ, Hamilton SP, Levinson DF, Lewis CM, Lewis G, Martin NG, Milaneschi Y, Mors O, Müller-Myhsok B, Penninx BWJH, Perlis RH, Pistis G, Potash JB, Preisig M, Shi J, Smoller JW, Streit F, Tiemeier H, Uher R, Van der Auwera S, Viktorin A, Weissman MM, MDD Working Group of the Psychiatric Genomics Consortium, Kendler KS, Flint J (2020):
    Minimal phenotyping yields genome-wide association signals of low specificity for major depression.
    Nature Genetics 52(4):437-447
    View abstract
  • Dwyer DB, Kalman JL, Budde M, Kambeitz J, Ruef A, Antonucci LA, Kambeitz-Ilankovic L, Hasan A, Kondofersky I, Anderson-Schmidt H, Gade K, Reich-Erkelenz D, Adorjan K, Senner F, Schaupp S, Andlauer TFM, Comes AL, Schulte EC, Klöhn-Saghatolislam F, Gryaznova A, Hake M, Bartholdi K, Flatau-Nagel L, Reitt M, Quast S, Stegmaier S, Meyers M, Emons B, Haußleiter IS, Juckel G, Nieratschker V, Dannlowski U, Yoshida T, Schmauß M, Zimmermann J, Reimer J, Wiltfang J, Reininghaus E, Anghelescu IG, Arolt V, Baune BT, Konrad C, Thiel A, Fallgatter AJ, Figge C, von Hagen M, Koller M, Lang FU, Wigand ME, Becker T, Jäger M, Dietrich DE, Scherk H, Spitzer C, Folkerts H, Witt SH, Degenhardt F, Forstner AJ, Rietschel M, Nöthen MM, Mueller N, Papiol S, Heilbronner U, Falkai P, Schulze TG, Koutsouleris N (2020):
    An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.
    JAMA Psychiatry 77(5):523-533
    View abstract
  • Comes AL, Czamara D, Adorjan K, Anderson-Schmidt H, Andlauer TFM, Budde M, Gade K, Hake M, Kalman JL, Papiol S, Reich-Erkelenz D, Klöhn-Saghatolislam F, Schaupp SK, Schulte EC, Senner F, Juckel G, Schmauß M, Zimmermann J, Reimer J, Reininghaus E, Anghelescu IG, Konrad C, Thiel A, Figge C, von Hagen M, Koller M, Dietrich DE, Stierl S, Scherk H, Witt SH, Sivalingam S, Degenhardt F, Forstner AJ, Rietschel M, Nöthen MM, Wiltfang J, Falkai P, Schulze TG, Heilbronner U (2020):
    The Role of Environmental Stress and DNA Methylation in the Longitudinal Course of Bipolar Disorder
    International Journal of Bipolar Disorders 8(1):9
    View abstract
  • Arloth J, Eraslan G, Andlauer TFM, Martins J, Iurato S, Kühnel B, Waldenberger M, Frank J, Gold R, Hemmer B, Luessi F, Nischwitz S, Paul F, Wiendl H, Gieger C, Heilmann-Heimbach S, Kacprowski T, Laudes M, Meitinger T, Peters A, Rawal S, Strauch K, Lucae S, Müller-Myhsok B, Rietschel M, Theis FJ, Binder EB, Mueller NS (2020):
    DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.

    PLOS Computational Biology, doi:10.1371/journal.pcbi.1007616
    View abstract
  • Three additional publications as part of the MDD Working Group of the Psychiatric Genomics Consortium:
    • Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.
      Molecular Psychiatry doi:10.1038/s41380-020-0689-5
      View abstract
    • Genome-wide Gene-Environment Analyses of Major Depressive Disorder and Reported Lifetime Traumatic Experiences in UK Biobank.
      Molecular Psychiatry 25(7):1430-1446
      View abstract
    • A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank.
      Nature Communications 11(1):2301
      View abstract

2019

  • Cross-Disorder Group of the Psychiatric Genomics Consortium:
    Lee PH, Anttila V, Won H, Feng YA, Rosenthal J, Zhu Z, Tucker-Drob EM, Nivard MG, Grotzinger AD, Posthuma D, Wang MM, Yu D, Stahl EA, …, …, Andlauer TFM, …, …, Smoller JW (2019):
    Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
    Cell 179(7):P1469-1482.e11
    View abstract
  • Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, González MJ, Gil Flores S, Cabaleiro Fabeiro FJ, del Río Noriega F, Perez Perez F, Haro González J, Orozco Diaz G, de Diego-Otero Y, Moreno-Kuestner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon C, Kogevinas M, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rivas F, Mayoral F, Müller-Myhsok B, Forstner AJ, Nöthen MM, Rietschel M (2019):
    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
    Molecular Psychiatry 26:1286-1298 (2021)
    View abstract
    …or read the German press release
  • International Multiple Sclerosis Genetics Consortium:
    Patsopoulos NA, Baranzini SE, Santaniello A, Shoostari P, Cotsapas C, Wong G, Beecham AH, James T, Replogle J, Vlachos IS, McCabe C, Pers TH, Brandes A, White C, Keenan B, Cimpean M, Winn P, Panteliadis IP, Robbins A, Andlauer TFM, …, …, De Jager PL (2019):
    Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.

    Science 365(6460):eaav7188
    View abstract
  • Adorjan K, Mekonnen Z, Tessema F, Ayana M, Degenhardt F, Hoffmann P, Fricker N, Widmann M, Riedke H, Toennes S, Soboka M, Suleman S, Andlauer TFM, Tesfaye M, Rietschel M, Susser E, Odenwald M, Schulze TG, Mattheisen M (2019):
    Genotype-phenotype feasibility studies on khat abuse, traumatic experiences and psychosis in Ethiopia.
    Psychiatric Genetics 30(1):34-38
    View abstract
  • Comes AL, Senner F, Budde M, Adorjan K, Anderson-Schmidt H, Andlauer TFM, Gade K, Hake M, Heilbronner U, Kalman JL, Reich-Erkelenz D, Klöhn-Saghatolislam F, Schaupp SK, Schulte EC, Juckel G, Dannlowski U, Schmauß M, Zimmermann J, Reimer J, Reininghaus E, Anghelescu IG, Arolt V, Baune BT, Konrad C, Thiel A, Fallgatter AJ, Nieratschker V, Figge C, von Hagen M, Koller M, Becker T, Wigand ME, Jäger M, Dietrich DE, Stierl S, Scherk H, Spitzer C, Folkerts H, Witt SH, Degenhardt F, Forstner AJ, Rietschel M, Nöthen MM, Wiltfang J, Falkai P, Schulze TG, Papiol S (2019):
    The genetic relationship between educational attainment and cognitive performance in major psychiatric disorders.
    Translational Psychiatry 9(1):210
    View abstract
  • Glanville KP, Coleman JRI, Hanscombe KB, Euesden J, Choi SW, Purves KL, Breen G, Air TM, Andlauer TFM, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Buttenschøn HN, Colodro-Conde L, Dannlowski U, Direk N, Dunn EC, Forstner AJ, Geus EJd, Grabe HJ, Hamilton SP, Jones I, Jones LA, Knowles JA, Kutalik Z, Levinson DF, Lewis G, Lind PA, Lucae S, Magnusson PK, McGuffin P, McIntosh AM, Milaneschi Y, Mors O, Mostafavi S, Müller-Myhsok B, Pedersen NL, Penninx BW, Potash JB, Preisig M, Ripke S, Shi J, Shyn SI, Smoller JW, Streit F, Sullivan PF, Tiemeier H, Uher R, Auwera SVd, Weissman MM, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, O’Reilly PF, Lewis CM (2019):
    Classical HLA alleles and C4 haplotypes are not significantly associated with depression.
    Biological Psychiatry 87(5):419–430
    View abstract
  • Paul R, Andlauer TFM, Czamara D, Hoehn D, Lucae S, Pütz B, Lewis CM, Uher R, Müller-Myhsok B, Ising M, Sämann PG (2019):
    Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models.
    Translational Psychiatry 9:187
    View abstract
  • van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E, DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D; GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H (2019):
    A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
    Acta Neuropathologica 138(2):237-250
    View abstract
  • International Multiple Sclerosis Genetics Consortium:
    Madireddy L, Patsopoulos NA, Cotsapas C, Bos SD, Beecham A, McCauley J, Kim K, Jia X, Santaniello A, Caillier SJ, Andlauer TFM, Barcellos LF, Berge T, Bernardinelli L, Martinelli-Boneschi F, Booth DR, Briggs F, Celius EG, Comabella M, Comi G, Cree BAC, D’Alfonso S, Dedham K, Duquette P, Efthimios D, Esposito F, Fontaine B, Gasperi C, Goris A, Dubois B, Gourraud PA, Hadjigeorgiou G, Haines J, Hawkins C, Hemmer B, Hintzen R, Horakova D, Isobe N, Kalra S, Kira JI, Khalil M, Kockum I, Lill CM, Lincoln MR, Luessi F, Martin R, Oturai A, Palotie A, Pericak-Vance MA, Henry R, Saarela J, Ivinson A, Olsson T, Taylor BV, Stewart GJ, Harbo HF, Compston A, Hauser SL, Hafler DA, Zipp F, De Jager P, Sawcer S, Oksenberg JR, Baranzini SE (2019):
    A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis.
    Nature Communications 10:2236
    View abstract
  • Meller T, Schmitt S, Stein F, Brosch K, Mosebach J, Yüksel D, Zaremba D, Grotegerd D, Dohm K, Meinert S, Förster K, Redlich R, Opel N, Repple J, Hahn T, Jansen A, Andlauer TFM, Forstner AJ, Heilmann-Heimbach S, Streit F, Witt SH, Rietschel M, Müller-Myhsok B, Nöthen MM, Dannlowski U, Krug A, Kircher T, Nenadić I (2019):
    Associations of schizophrenia risk genes ZNF804A and CACNA1C with schizotypy and modulation of attention in healthy subjects.
    Schizophrenia Research 208:67-75.
    View abstract
  • Gialluisi A, Andlauer TFM, Mirza-Schreiber N, Moll K, Becker J, Hoffmann P, Ludwig KU, Czamara D, St Pourcain B, Brandler W, Honbolygó F, Tóth D, Csépe V, Huguet G, Morris AP, Hulslander J, Willcutt EG, DeFries JC, Olson RK, Smith SD, Pennington BF, Vaessen A, Maurer U, Lyytinen H, Peyrard-Janvid M, Leppänen PHT, Brandeis D, Bonte M, Stein JF, Talcott JB, Fauchereau F, Wilcke A, Francks C, Bourgeron T, Monaco AP, Ramus F, Landerl K, Kere J, Scerri TS, Paracchini S, Fisher SE, Schumacher J, Nöthen MM, Müller-Myhsok B, Schulte-Körne G (2019):
    Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.
    Translational Psychiatry 9(1):77
    View abstract
  • Anderson-Schmidt H, Gade K, Malzahn D, Papiol S, Budde M, Heilbronner U, Reich-Erkelenz D, Adorjan K, Kalman JL, Senner F, Comes AL, Flatau L, Gryaznova A, Hake M, Reitt M, Schmauß M, Juckel G, Reimer J, Zimmermann J, Figge C, Reininghaus E, Anghelescu IG, Konrad C, Thiel A, von Hagen M, Koller M, Stierl S, Scherk H, Spitzer C, Folkerts H, Becker T, Dietrich DE, Andlauer TFM, Degenhardt F, Nöthen MM, Witt SH, Rietschel M, Wiltfang J, Falkai P, Schulze TG (2019):
    The influence of religious activity and polygenic schizophrenia risk on religious delusions in schizophrenia.
    Schizophrenia Research 210, 255-261
    View abstract
  • Six additional publications as part of the MDD Working Group of the Psychiatric Genomics Consortium:
    • Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
      Nature Communications 10:2548
      View abstract
    • Identification of common genetic risk variants for autism spectrum disorder.
      Nature Genetics 51, 431–444
      View abstract
    • The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.
      Biological Psychiatry 88(2):169-184
      View abstract
    • Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study.
      JAMA Psychiatry 76(4):399-408
      View abstract
    • Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy.
      American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 180(1):35-45
      View abstract
    • Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium.
      Psychological Medicine 49(7):1218-1226
      View abstract

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